Ingenious Beauty Research Papers

There is considerable research on each of our three amazing ingredients and their positive effects on the skin and body. We have selected the six most recent, clinical, placebo-controlled trials for each. If you would like the full list, please email: [email protected]

Collagen Peptide

  1. Cosgrove, M.C. et al., 2007, Dietary nutrient intakes and skin-aging appearance among middle-aged American women. American Journal of Clinical Nutrition, 86 (4): 1225-1231
  2. Asserin, J. et al., 2015. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, doi: 10.1111/jocd.12174
  3. Clinical study, Cosderma, France, 2012
  4. Clinical study YNTKK 2008 4144, Souken, Japan
  5. Clinical study 2008 A00654 51, Dermscan, France
  6. Ohara H, Ichikawa S, Matsumoto H, Akiyama M, Fujimoto N, Kobayashi T, Tajima S, 2010. Collagen derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. J Dermato 374: 330-338

Natural Astaxanthin

  1. Tominaga K et al., Cosmetic benefits of astaxanthin on human subjects. Acta Biochim Pol. 2012;59(1):43-7.
  2. Suganuma K et al., Anti-aging and functional improvement effects for the skin by functional food intake: clinical effects on skin by oral ingestion of preparations containing Astaxanthin and Vitamins C and E. Jichi Medical University Journal. 2012;35:25-33.
  3. Tominaga K et al., Cosmetic effects of astaxanthin for all layers of skin. Food Style 21. 2009;13(10):25-9.
  4. Satoh A et al., Effect of the intake of astaxanthin containing Haematococcus pluvialis extract on the severity, immunofunction and physiological function in patients with atopic dermatitis. Jpn J Environ Dermatol Cutan Allergol. 2009;3(5):429-38.
  5. Yamashita E, The effects of a dietary supplement containing astaxanthin on skin condition. Carotenoid Science. 2006;10:91-5.
  6. Camera E et al. Astaxanthin, canthaxanthin and b-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Experimental Dermatology, 18, 222231

Hyaluronic Acid

  1. Meyer LJM et al. Age-dependent changes of hyaluronan in human skin. Journal of Investigative Dermatology. 1994;102:385-389.
  2. Sakai S et al. Hyaluronan exists in the normal stratum corneum. Journal of Investigative Dermatology. 2000;114:1184-1187.
  3. Meyer LJM et al. Reduced hyaluronan in keloid tissue and cultured keloid fibroblasts. Journal of Investigative Dermatology. 2000;114:953-959.
  4. Wakayama S, presenter. Clinical study on demonstrates improvement of skin moisture content. Poster session presented at the March 2009 Nutracon and SupplyExpo conference, Anaheim, CA.
  5. Tashiro T et al. Oral administration of polymer hyaluronic acid alleviates symptoms of knee osteoarthritis: a double blind, placebo controlled study over a 12 month period. Scientific World Journal. 2012;2012: 167928
  6.  Mariko Oe et al. Oral hyaluronan relieves knee pain: a review. Nutr J. 2016; 15: 11.

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